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Synthesis, biological evaluation, and radioiodination of halogenated closo-carboranylthymidine analogues
Faculty
Science
Year:
2011
Type of Publication:
ZU Hosted
Pages:
Authors:
Ahmed Khalil Elsayed Khalil
Staff Zu Site
Abstract In Staff Site
Journal:
Nucleosides, Nucleotides and Nucleic Acids ACS
Volume:
Keywords :
Synthesis, biological evaluation, , radioiodination , halogenated closo-carboranylthymidine
Abstract:
The synthesis and initial biological evaluation of 3-carboranylthymidine analogues (3CTAs) that are (radio)halogenated at the closo-carborane cluster are described. Radiohalogenated 3CTAs have the potential to be used in the radiotherapy an
Author Related Publications
Ahmed Khalil Elsayed Khalil, "Iodine monochloride facilitated deglycosylation, anomerization, and isomerization of 3-substituted thymidine analogues.", Taylor & Francis, 2014
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Ahmed Khalil Elsayed Khalil, "Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer.", Elsevier, 2015
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Ahmed Khalil Elsayed Khalil, ": Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans.", Elsevier, 2014
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Ahmed Khalil Elsayed Khalil, "2'-Chloro,2'-fluoro ribonucleotide prodrugs with potent pan-genotypic activity against Hepatitis C Virus replication in culture", ACS, 2017
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Ahmed Khalil Elsayed Khalil, "Synthesis and biological evaluation of aminothiazoles against Histoplasma capsulatum and Cryptococcus neoformans.", Elsevier, 2018
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