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Delusions and hallucinations in Alzheimer's disease: Review of the brain decade
Faculty
Medicine
Year:
2003
Type of Publication:
Article
Pages:
388-401
Authors:
Bassiony, MM, Lyketsos, CG
DOI:
10.1176/appi.psy.44.5.388
Journal:
PSYCHOSOMATICS AMER PSYCHIATRIC PRESS, INC
Volume:
44
Research Area:
Psychiatry; Psychology
ISSN
ISI:000185081100005
Keywords :
Delusions , hallucinations , Alzheimer's disease: Review , , brain
Abstract:
The authors reviewed studies published from 1990 to 2001 that address the epidemiology, phenomenology, course, etiology, assessment, and treatment of delusions and hallucinations in Alzheimer's disease. The prevalence of delusions in Alzheimer's disease patients ranged from 16\% to 70\% (median = 36.5\%) in the reviewed reports, and the prevalence of hallucinations ranged from 4\% to 76\% (median = 23\%). Delusions and hallucinations tended to persist over time, tended to recur often during the course of Alzheimer's disease, and were associated with socio-demographic and clinical correlates that differed from one study to another and with substantial consequences such as functional impairment and aggression. Psychosocial methods and both typical and atypical antipsychotics are effective in the treatment of delusions and hallucinations in Alzheimer's disease.
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