A Direct Synthesis for a New Series of 2-Oxo(thioxo)nicotinonitrile Nucleosides as Antimicrobial Agents

Faculty Science Year: 2019
Type of Publication: ZU Hosted Pages: 1-8
Authors:
Ahmed Heussein Mostafa
Journal: Current Organic Synthesis Wiley Volume: 14
Keywords : , Direct Synthesis , , , Series , 2-Oxo(thioxo)nicotinonitrile Nucleosides , Antimicrobial Agents    
Abstract:
A facile synthesis of a new series of cyclic and acyclic nucleosides of polyfunctionalized 2-oxo(thioxo) nicotinonitrile derivatives 1 and 2 was performed. Glycosylation of 2-pyridone 1 and 2-thiopyridone 2 with glycosyl/galactosyl bromid
    
     
 
       

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