A new series of hydrazide-hydrazones based 2-oxonicotinonitriles as antimicrobial agents: Design, synthesis and antimicrobial evaluation

Faculty Science Year: 2019
Type of Publication: ZU Hosted Pages: 164-176
Authors:
Ahmed Heussein Mostafa
Journal: Journal of Molecular Liquids ٍspringer Volume: 273
Keywords : , , series , hydrazide-hydrazones based 2-oxonicotinonitriles , antimicrobial agents: Design, synthesis    
Abstract:
Regiospecific alkylation of 2-oxonicotinonitriles 1a,b with ethyl bromoacetate followed by hydrozinolysis afforded acetic acid hydrazides 3a,b. The latter compounds were condensed with a variety of carbonyl containing compounds to give
   
     
 
       

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