Synthesis, Characterization and Biological Evaluation of 6-Ethoxy-2-oxo(thioxo)-4- Phenyl-1,2-dihydropyridine-3,5-dicarbonitrile Nucleosides

Faculty Science Year: 2017
Type of Publication: ZU Hosted Pages: 125-131
Authors:
Ahmed Heussein Mostafa
Journal: Journal of Pharmaceutical and Applied Chemistry Banthaman publisher Volume: 4
Keywords : Synthesis, Characterization , Biological Evaluation , 6-Ethoxy-2-oxo(thioxo)-4- Phenyl-1,2-dihydropyridine-3,5-dicarbonitrile Nucleosides    
Abstract:
A series of cyclic and acyclic nucleosides of polyfunctionalized 2-oxo(thiooxo)nicotinonitrile derivatives 1 and 2 were synthesized by reaction of compounds 1 or 2 with glycosyl bromides or other alkylating agents in the presence of K2CO3
    
     
 
       

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