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Non-immune hydrops: Qatar experience
Faculty
Medicine
Year:
2013
Type of Publication:
Article
Pages:
449-453
Authors:
Hasnani-Samnani, Zohra, Mahmoud, Mohamed Ibrahim Mohamed, Farid, Ibrahim, Al Naggar, Eman, Ahmed, Badreldeen
DOI:
10.3109/14767058.2012.733781
Journal:
JOURNAL OF MATERNAL-FETAL \& NEONATAL MEDICINE INFORMA HEALTHCARE
Volume:
26
Research Area:
Obstetrics \& Gynecology
ISSN
ISI:000314974900003
Keywords :
Congenital intrauterine infection, congenital heart disease, non-immune hydrops
Abstract:
Objective: To describe the presenting signs, diagnostic findings, and outcomes of 64 cases of non-immune hydrops fetalis (NIHF) cases seen in Women's Hospital, Qatar during the years 2003-2011. Method: A retrospective chart review of patients with signs suggesting of NIHF was done. A detailed scan was performed and karyotyping and detailed investigations were offered. Results: Average maternal age at diagnosis was 31 years. Fifty-six percent of the patients were diagnosed during the 2nd trimester. Most common presenting signs were: ascites, pleural effusion, scalp edema, skin edema, pericardial effusion, generalize edema and cystic hygroma. Two patients were positive for PV B19 infection. Fetal karyotyping performed in 78\% of the patients showed abnormal chromosomes in 9 cases. Three patients showed fetal anemia with abnormal peak systolic velocity of the medial cerebral artery (MCA-PSV). Seventeen (27\%) fetuses survived the perinatal period with live births occurring between gestational ages 30-41 weeks. Ten (59\%) of the 17 babies survived post delivery (6 months post survival data). Major identifiable abnormalities that might have caused symptoms of hydrops were cardiac (23.43\%), and chromosomal (14\%). Conclusion: Non-immune hydrops fetalis is a complex problem. Establishment of a clear procedure for the follow up of such patients is extremely important.
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