Pyridazine derivatives and related compounds. Part 11: Synthesis of some pyrimido{[}4 `,5 `: 4,5]thieno{[}2,3-c]pyridazines

Faculty	Science	Year:	2004
Type of Publication:	Article	Pages:	2245-2252
Authors:	DEEB, A, El-Abbasy, M, Kotb, M	DOI:	10.1080/10426500490475175
Journal:	PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS TAYLOR \& FRANCIS LTD	Volume:	179
Research Area:	Chemistry	ISSN	ISI:000225266100010
Keywords :	Pyridazine derivatives , related compounds. Part , Synthesis
Abstract:	3-Substituted pyrimido{[}4',5':4,5]thieno{[}2,3-c]pyridazine-2,4-di-ones and 3-amino-2-methylpyrimidol{[}4',5':4,5]thieno{[}2,3-c] pyridazine-6-carboxylate 1. Reaction of amino ester 1 with phenyl isothiocynate affords thiourea derivative 10 which undergo further transformation to the related fused heterocyclic systems.
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