Involvement of Gβγ subunits of Gi protein coupled with S1P receptor on multivesicular endosomes in F-actin formation and cargo sorting into exosomes.

Faculty Agriculture Year: 2018
Type of Publication: ZU Hosted Pages:
Authors:
Shaimaa Mohamed Mohamed Badawi
Journal: Journal of Biological Chemistry Journal of Biological Chemistry Volume:
Keywords : Involvement , , subunits , , protein coupled with , receptor    
Abstract:
Abstract Exosomes play a critical role in cell-to-cell communication by delivering cargo molecules to recipient cells. However, the mechanism underlying the generation of the exosomal multivesicular endosome (MVE) is one of the mysteries i
    
     
 
       

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  • Shaimaa Mohamed Mohamed Badawi, "DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling.", Nature Science Reports, 2017 More
  • Shaimaa Mohamed Mohamed Badawi, "Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G-protein signaling.", Journal of Biological Chemistry, 2018 More
  • Shaimaa Mohamed Mohamed Badawi, "Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact.", Nature Scientific Reports, 2017 More
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  • Shaimaa Mohamed Mohamed Badawi, "Phospholipase D is Dispensable for Epidermal Growth Factor-Induced Chemotaxis.", Journal of Medical Science, 2017 More

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