DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling.

Faculty Agriculture Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Shaimaa Mohamed Mohamed Badawi
Journal: Nature Science Reports Nature Science Reports Volume:
Keywords : DHHC5-mediated palmitoylation , , receptor subtype , determines G-protein    
Abstract:
Abstract Sphingosine 1-phosphate (S1P) is a pleiotropic lipid mediator involved in the regulation of immune cell trafficking and vascular permeability acting mainly through G-protein-coupled S1P receptors (S1PRs). However, mechanism underl
    
     
 
       

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  • Shaimaa Mohamed Mohamed Badawi, "Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact.", Nature Scientific Reports, 2017 More
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  • Shaimaa Mohamed Mohamed Badawi, "Phospholipase D is Dispensable for Epidermal Growth Factor-Induced Chemotaxis.", Journal of Medical Science, 2017 More

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