DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling.

Faculty Agriculture Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Shaimaa Mohamed Mohamed Badawi
Journal: Nature Science Reports Nature Science Reports Volume:
Keywords : DHHC5-mediated palmitoylation , , receptor subtype , determines G-protein    
Abstract:
Abstract Sphingosine 1-phosphate (S1P) is a pleiotropic lipid mediator involved in the regulation of immune cell trafficking and vascular permeability acting mainly through G-protein-coupled S1P receptors (S1PRs). However, mechanism underl
    
     
 
       

Author Related Publications

  • Shaimaa Mohamed Mohamed Badawi, "Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G-protein signaling.", Journal of Biological Chemistry, 2018 More
  • Shaimaa Mohamed Mohamed Badawi, "Involvement of Gβγ subunits of Gi protein coupled with S1P receptor on multivesicular endosomes in F-actin formation and cargo sorting into exosomes.", Journal of Biological Chemistry, 2018 More
  • Shaimaa Mohamed Mohamed Badawi, "Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact.", Nature Scientific Reports, 2017 More
  • Shaimaa Mohamed Mohamed Badawi, "Impairment of PDGF-induced chemotaxis by extracellular α-synuclein through selective inhibition of Rac1 activation.", Nature Scientific Reports, 2016 More
  • Shaimaa Mohamed Mohamed Badawi, "Phospholipase D is Dispensable for Epidermal Growth Factor-Induced Chemotaxis.", Journal of Medical Science, 2017 More

Department Related Publications

  • Hytham Ali Badr Elmorsy, "Live Cell Integrated Surface Plasmon Resonance Biosensing Approach to Mimic the Regulation of Angiogenic Switch upon Anti-Cancer Drug Exposure", American Chemical Society, 2014 More
  • Hytham Ali Badr Elmorsy, "Lectin approaches for glycoproteomics in FDAapproved cancer biomarkers", Informa UK, 2014 More
  • Ibrahim Eid Elsayed Mohamed Eleissawy, "Impact of rice straw mulching on water consumption and productivity of orange trees [Citrus sinensis (L.) Osbeck]", Elsevier, 2024 More
  • Taha Fathy Taha Ibrahiem, "Expression Profile of Redox Active Secondary Metabolites Related Genes Obtained by Transcriptome Sequencing Under Salt and Drought Stress in Sweet Potato", دولي, 2018 More
  • Taha Fathy Taha Ibrahiem, "In Vitro Bio-Medical Studies on Psidium Guajava Leaves", دولي, 2019 More
Tweet