A Facile Synthesis of N- and O-alkylated Nicotinonitriles and its 2-methoxy 1,2,3
triazole Candidates as Potential Anticancer and Antimicrobial Agents

Faculty	Science	Year:	2018
Type of Publication:	ZU Hosted	Pages:	6-10
Authors:	Ahmed Heussein Mostafa Staff Zu Site Abstract In Staff Site
Journal:	Der Pharma Chemica Elsiver	Volume:	10

Keywords :	, Facile Synthesis , , , O-alkylated Nicotinonitriles , , 2-methoxy 1,2,3 triazole
Abstract:	A series of N- and O- alkylated nicotinonitriles was reported. Base mediate alkylation of nicotinonitriles 1a-c with chloroacetonitrile, allyl bromide and propargyl bromide produced N- and O- alkylated nicotinonitrile derivatives 3-6. Reac

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