Design and Synthesis of Hydrazide-Hydrazones Based 2-Oxonicotinonitrile Derivatives as Potential Antimicrobial Agents

Faculty Science Year: 2018
Type of Publication: ZU Hosted Pages: 125-131
Authors:
Ahmed Heussein Mostafa
Journal: Journal of Pharmaceutical and Applied Chemistry natural science Volume: 4
Keywords : Design , Synthesis , Hydrazide-Hydrazones Based 2-Oxonicotinonitrile Derivatives    
Abstract:
Synthesis and antimicrobial screening of new series of hydrazide-hydrazones were described. Where, regiospacific alkylation of 2-oxonicotinonitriles1a,b with ethyl bromoacetate followed by hydrozinolys is afforded acetic acid hydrazides3a,b
    
     
 
       

Author Related Publications

  • Ahmed Heussein Mostafa, "Evaluation of the Curative and Protective Role of Fresh Chicory Juice in Treatment of Hepatic Fibrosis in Male Albino Rats", Scoups, 2021 More
  • Ahmed Heussein Mostafa, "Efficient biocontrol of Spodoptera littoralis by Aspergillus nidulans, an endophyte of Lantana camara", ٍSpringer, 2020 More
  • Ahmed Heussein Mostafa, "Synthesis and Biological Evaluation of Glycosides and AcyclicNucleosides Derived 2-Oxonicotinonitriles", Wiely, 2019 More
  • Ahmed Heussein Mostafa, "Novel Triazole-, Oxadiazole-, and Pyrazole-Nicotinonitrile Hybrids: Synthesis, DFT Study, Molecular Docking, and Antimicrobial Activity", ٍSpringer, 2022 More
  • Ahmed Heussein Mostafa, "Synthesis and biological evaluation of 2-Oxo/thioxoquinoxaline and 2-Oxo/thioxoquinoxaline-based nucleoside analogues", EBSCO, 2016 More

Department Related Publications

  • Hassan AbdelFattah Mohammed, "Design and synthesis of some tricyclic pyrimidines and triazines via cycloaddition and intermolecular cyclization of cyclic amidine", Springer, 2017 More
  • Mohamed Yousry Elsayed ebrahim, "Synthesis of new drug model has an effective antimicrobial and antitumors by combination of cephalosprin antibiotic drug with silver (I) ion in nano scale range: chemical, physical and biological studies", Elsevier, 2017 More
  • Amr Lotfy Saber Hefny, "Liquid Chromatographic and Potentiometric Methods for the Determination of Oxomemazine in Pharmaceutical Preparations", Open Science, 2017 More
  • Hassan AbdelFattah Mohammed, "O-glycosylation/alkylation and antimicrobial activity of 4,6-diaryl-2-oxonicotinonitrile derivatives", Wilyinterscience, 2017 More
  • Reda Ahmed aly Hjam, "O-glycosylation/alkylation and antimicrobial activity of 4,6-diaryl-2-oxonicotinonitrile derivatives", Wilyinterscience, 2017 More
Tweet