On the reactivity of platinum(IV) complexes: Synthesis and spectroscopic studies of platinum(IV) complexes with hypoxanthine

Na-2{[}PtCI6] was found to react with (HypH)(ClH2O)-H-. (2) (Hyp=hypoxanthine) in aqueous solution at room temperature yielding (HypH)(2){[}PtCl6] (3). The same compound was obtained from hexachloroplatinic acid and hypoxanthine. Performing this reaction in methanol at 50 degrees C complex formation took place yielding the hypoxanthine complex {[}PtCl4(HYP)(2)] (4). Both compounds were isolated in good yields as faint orange (3) and yellow (4) precipitates, respectively and characterized by microanalyses, IR and NMR (H-1, C-13, (195)pt) spectroscopies as well as thermal analysis. Based on the data obtained an octahedral molecular structure is proposed for complex 4 with two hypoxanthine ligands coordinated through N7 to platinum(IV). (c) 2005 Elsevier B.V. All rights reserved.