Pyridazine derivatives and related compounds Part 19: The synthesis of different heterocycles from ethyl 5-amino-3,4-diphenylthieno{[}2,3-c]pyridazine-6-carboxylate

Faculty Science Year: 2006
Type of Publication: Article Pages: 879-890
Authors: DOI: 10.1080/10426500500272145
Journal: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS TAYLOR \& FRANCIS LTD Volume: 181
Research Area: Chemistry ISSN ISI:000236358600018
Keywords : pyridazinotienothiazine, pyrimdothenopyridazine, substituted pyridothienopyridazine    
Abstract:
7-substituted pyrido{[}2',3':4,5] thieno{[}2,3-c]pyridazines and 6-substituted pyrimido{[}4',5':4,5]thieno{[}2,3-c]pyridazines were synthesized starting from ethyl 5-aminothieno{[}2,3-c]pyridazino-6-carboxylate 1. The reaction of amino ester 1 with benzoyl isothiocyanate affords thiourea derivative 8, which undergoes further transformation to the related fused heterocyclic systems.
   
  Online    
PDF  
       
Tweet