Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
New potentiometric sensors for creatinine
Faculty
Science
Year:
2006
Type of Publication:
Article
Pages:
253-257
Authors:
Elmosallamy, MAF
DOI:
10.1016/j.aca.2006.01.103
Journal:
ANALYTICA CHIMICA ACTA ELSEVIER SCIENCE BV
Volume:
564
Research Area:
Chemistry
ISSN
ISI:000236944600017
Keywords :
neutral carrier, crown ether, potentiometric sensors, lipophilic additives, creatinine determination, real samples
Abstract:
Three main types of creatinine potentiometric membrane sensors are described. They are based on the use of dibenzo-30-crown-10 (DB30C10) with potassium tetrakis(p-chlorophenyl)borate type (I), dibenzo-30-crown-10 alone type (II), and potassium tetrakis(p-chlorophenyl)borate alone type (III), incorporating in poly(vinyl chloride) matrix membrane plasticized with either o-nitrophenyl octyl ether or dioctylphthalate. The sensors are used for quantification of creatinine after soaking the membranes in 0.1 M creatinine solution for 2 days. The sensors show almost the same potentiometric response characteristics. Sensor type (I) exhibits Nernstian responses over a concentration range of 5.0 x 10(-5) mol l(-1)-1.0 X 10(-2) mol l(-1) creatinine with cationic slopes of 59.5 +/- 0.1 and 60 +/- 0.2 mV decade(-1) and detection limits of 1.1 x 10(-5) mol l(-1) and 8 x 10(-6) mol l(-1) creatinine, over the pH range of 3.5-6.5 and 3.5-7.0, for o-NPOE and DOP solvent mediators, respectively. Sensor type (II) displays Nernstian responses over a concentration range of 6.0 x 10(-5) mol l(-1)-1.0 X 10(-2) mol l(-1) creatinine with cationic slopes of 60.0 +/- 0.1 and 65.0 +/- 0.2 mV decade(-1) and detection limits of 1.5 x 10(-5) mol l(-1) and 1.4 x 10(-5) mol l(-1) creatinine over the pH range of 2.6-6.2 and 2.5-6.0, for o-NPOE and DOP solvent mediators, respectively. Sensortype (III) shows Nernstian responses over a concentration range of 7.0 x 10(-5) mol l(-1)-1.0 X 10(-2) mol l(-1) creatinine with cationic slopes of 60 +/- 0.1 and 62.0 +/- 0.2 mV decade(-1) and detection limits of 2.7 x 10(-5) mol l(-1) and 2.0 x 10(-1) mol l(-1) creatinine over the pH range of 2.5-6.0, for o-NPOE and DOP solvent mediators, respectively. The response times of the sensors for 10(-3) mol l(-1) creatinine solution are instantaneous (4-10 s). The sensors show long-term stability with life span of similar to 6 months. The sensors are used for determination of serum creatinine of rats (Rattus Norvigicus) with mean R.S.D. of 2.62\%, and the results agreed well with the Jaffe kinetic method. (c) 2006 Elsevier B.V. All rights reserved.
Online
PDF
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف