Michael Cyclization of Polarized Systems: Synthesis and in vitro Anti-Diabetic Evaluation of Some Novel Pyrimidine, Pyridine, Pyrazole and Pyrazolo[3,4-b]Pyridine Derivatives

Faculty	Science	Year:	2017
Type of Publication:	ZU Hosted	Pages:	461-469
Authors:	Essam AbdulGhani AbdelHalim Staff Zu Site Abstract In Staff Site
Journal:	Croatica Chemica Acta Croatian Chemical Society, with co-publishers Faculty of Science, University of Zagreb, and Ruđer Bošković Institute, Zagreb since 1927	Volume:	90

Keywords :	Michael Cyclization , Polarized Systems: Synthesis , , vitro
Abstract:	Various interesting heterocycle skeletons were synthesized via Michael type addition reaction with 1,2; 1,3-bidentate nitrogen and carbon nucleophiles. Cycloaddition of different α,β–unsaturated systems afforded bromopyrimidinone 3/5, bromo

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