Michael Cyclization of Polarized Systems: Synthesis and in vitro Anti-Diabetic Evaluation of Some Novel Pyrimidine, Pyridine, Pyrazole and Pyrazolo[3,4-b]Pyridine Derivatives

Faculty Science Year: 2017
Type of Publication: ZU Hosted Pages: 461-469
Authors:
Journal: Croatica Chemica Acta Croatian Chemical Society, with co-publishers Faculty of Science, University of Zagreb, and Ruđer Bošković Institute, Zagreb since 1927 Volume: 90
Keywords : Michael Cyclization , Polarized Systems: Synthesis , , vitro    
Abstract:
Various interesting heterocycle skeletons were synthesized via Michael type addition reaction with 1,2; 1,3-bidentate nitrogen and carbon nucleophiles. Cycloaddition of different α,β–unsaturated systems afforded bromopyrimidinone 3/5, bromo
   
     
 
       

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