Identification of Fhit as a post-transcriptional effector of Thymidine Kinase 1 expression

Faculty Medicine Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Seham Mahrous Zaki Nassr
Journal: Biochimica et Biophysica Acta : www.elsevier.com/locate/bbagrmScienceDirect Volume: 1860 (2017) 374–382
Keywords : Identification , Fhit , , post-transcriptional effector , Thymidine Kinase , expression    
Abstract:
FHIT is a genome caretaker gene that is silenced in N50% of cancers. Loss of Fhit protein expression promotes accumulation of DNA damage, affects apoptosis and epithelial-mesenchymal transition, though molecular mechanisms underlying thes
    
     
 
       

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