Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Mohammed Alhuseiny Abdelhamid Elsadek
Journal: Bioorganic & Medicinal Chemistry Letters www.elsevier.com/locate/bmcl Volume:
Keywords : Synthesis , evaluation , 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines , Bcl-2 inhibitory anticancer    
Abstract:
A series of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines 8a–j has been designed, synthesized and tested in vitro as potential pro-apoptotic Bcl-2-inhibitory anticancer agents based on our previous lead compound 8a. Synthesis of the t
    
     
 
       

Author Related Publications

  • Mohammed Alhuseiny Abdelhamid Elsadek , "Methods For Chemical Analysis Of Certain Penicillin Derivateves", لايوجد, 1900 More
  • Mohammed Alhuseiny Abdelhamid Elsadek , "Continuation For Chemical Methods For Analysis of Some Antibiotics", لايوجد, 1900 More
  • Mohammed Alhuseiny Abdelhamid Elsadek , "Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach", www.elsevier.com/locate/JMGM, 2017 More
  • Mohammed Alhuseiny Abdelhamid Elsadek , "Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach", www.elsevier.com/locate/JMGM, 2017 More
  • Mohammed Alhuseiny Abdelhamid Elsadek , "Synthesis and EPR-spectroscopic characterization of the perchlorotriarylmethyl tricarboxylic acid radical (PTMTC) and its 13C labelled analogue (13C-PTMTC)", ROYAL SOCIETY OF CHEMISTRY, 2017 More

Department Related Publications

  • Abdallah Ahmed Abdallah Elshanawany, "Development and Validation of LC Method for Simultaneous Determination of Two binary mixtures ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "HPLC Determination of Sulfamethoxazol and trimethoprime and other additive in suspention formulation ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Quantitative determination of ofloxacin, and ciprofloxacin hydrochloride with some related substances in pharmaceutical preparations using HPLC ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Synthesis and preliminary testing of some anthranilic acid derivatives as antiiflammatory ,Analgesic and antipyretic agents. ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Differential first derivative determination of acetylsalicylic acid in the presence of caffeine ", لايوجد, 1900 More
Tweet