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PARP inhibition ameliorates nephropathy in an animal model of type 2 diabetes: focus on oxidative stress, inflammation, and fibrosis
Faculty
Pharmacy
Year:
2017
Type of Publication:
ZU Hosted
Pages:
621-631
Authors:
Israa Mohamed Nagib Mohamed Zakarya
Staff Zu Site
Abstract In Staff Site
Journal:
Naunyn-Schmiedeberg's Archives of Pharmacology ٍSpringer
Volume:
6
Keywords :
PARP inhibition ameliorates nephropathy , , animal model
Abstract:
Poly(ADP-ribose) polymerase (PARP) enzyme contributes to nephropathy, a serious diabetic complication which may lead to end-stage renal disease. The study aims to investigate the effect of PARP over-activation on kidney functions in a type
Author Related Publications
Israa Mohamed Nagib Mohamed Zakarya, "PARP-1 inhibition alleviates diabetic cardiac complications in experimental animals", Elsevier, 2016
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Israa Mohamed Nagib Mohamed Zakarya, "Cardiovascular protection by DPP-4 inhibitors in preclinical studies: an updated review of molecular mechanisms", Springer Nature., 2022
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Israa Mohamed Nagib Mohamed Zakarya, "Linagliptin and Vitamin D3 Synergistically Rescue Testicular Steroidogenesis and Spermatogenesis in Cisplatin-Exposed Rats: The Crosstalk of Endoplasmic Reticulum Stress with NF-κB/iNOS Activation", MDPI, 2022
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Israa Mohamed Nagib Mohamed Zakarya, "Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products.", PLos One Corporation, USA, 2019
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Israa Mohamed Nagib Mohamed Zakarya, "Implication of endoplasmic reticulum stress and mitochondrial perturbations in remote liver injury after renal ischemia/reperfusion in rats: potential protective role of azilsartan", Taylor & Francis Online, 2024
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Department Related Publications
Mohammed Metwally Mohamed Metwallie, "Pathologic assessment of Azithromycin, Florfenicol and Trimethoprim-Sulfamethoxazole treatment in Pasteurella multocida infected rabbits.", zagazig university, 2013
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Mohamed Abdoh Mohamed Abdelatef Nasan, "Potential ameliorative role of N-acetylcysteine against testicular dysfunction induced by titanium dioxide in male albino rats", American Journal of Pharmacology and Toxicology, 2014
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Hytham Alieldeen Abdelbaset, "Fenpropathrin induces testicular damage, apoptosis, and genomic DNA damage in adult rats: Protective role of camel milk", Elsevier, 2019
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Mohammed Metwally Mohamed Metwallie, "Long-term intake of aspartame and hepatocellular injury in rabbit", zagzaig university fac of medicine, 2016
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Mohammed Metwally Mohamed Metwallie, "Comparable bio-evaluation of curcumin and chitosan-encapsulated curcumin nanoparticles against the reprotoxic potential of fenpropathrin pyrethroid in rats: Genomic and morphometric prospectives", Elsevier, 2023
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