PARP inhibition ameliorates nephropathy in an animal model of type 2 diabetes: focus on oxidative stress, inflammation, and fibrosis

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 621-631
Authors:
Israa Mohamed Nagib Mohamed Zakarya
Journal: Naunyn-Schmiedeberg's Archives of Pharmacology ٍSpringer Volume: 6
Keywords : PARP inhibition ameliorates nephropathy , , animal model    
Abstract:
Poly(ADP-ribose) polymerase (PARP) enzyme contributes to nephropathy, a serious diabetic complication which may lead to end-stage renal disease. The study aims to investigate the effect of PARP over-activation on kidney functions in a type
   
     
 
       

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