Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study

Faculty	Pharmacy	Year:	2017
Type of Publication:	ZU Hosted	Pages:
Authors:
Journal:	Bioorganic & Medicinal Chemistry Letters ELSEVIER	Volume:

Keywords :	Quinazolinone-based rhodanine-3-acetic acids , potent aldose reductase
Abstract:	A series of quinazolinone-based rhodanine-3-acetic acids was synthesized and tested for in vitro aldose reductase inhibitory activity. All the target compounds displayed nanomolar activity against the target enzyme. Compounds 3a, 3b, and 3e

Author Related Publications

Abdallah Ahmed Abdallah Elshanawany, "Development and validation of liquid chromatographic method for simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in human urine", لايوجد, 1900 More
Abdallah Ahmed Abdallah Elshanawany, "HPLC Determination of polymyxin sulphate, Benzalkonium chloride, and gramicidine in pharm.formulation ", لايوجد, 1900 More
Abdallah Ahmed Abdallah Elshanawany, "Synchronous Spectroflurimetric Determination of Famtidine,Fluconazole and Ketoconazole in bulk powder and in pharmaceutical dosages forms ", لايوجد, 1900 More
Abdallah Ahmed Abdallah Elshanawany, "Synthesis of 3- substituted (6-bromo-2-imidazo{4,5-b}pyridinyl)propionic acid as antiinflammatory agents. ", لايوجد, 1900 More
Abdallah Ahmed Abdallah Elshanawany, "Application of difference spectrophotometry to the nitrosation reaction in the assay of certain antipyretic drugs . ", لايوجد, 1900 More