Optimization of methotrexate loaded niosomes by Box–Behnken design: an understanding of solvent effect and formulation variability

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 1450-1459
Authors:
Nagia] Ahmed Alameen Elmgrab
Journal: Drug Development and Industrial Pharmacy Drug Development and Industrial Pharmacy Volume: 9
Keywords : Optimization , methotrexate loaded niosomes , Box–Behnken design:    
Abstract:
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential form
    
     
 
       

Author Related Publications

  • Nagia] Ahmed Alameen Elmgrab, "Novel Aqueous solvent based method for protein based nanoparticles.", Association of Biotechnology and pharmacy ®., 2008 More
  • Nagia] Ahmed Alameen Elmgrab, "Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability", A & V Publications India, 2012 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Nagia] Ahmed Alameen Elmgrab, "Ocular controlled delivery of brimonidine using liposomes as a particulate carrier", faculty of pharmac,y zagazig university, 2001 More
  • Nagia] Ahmed Alameen Elmgrab, "Enhancement of Antibacterial Activity of Tetracycline Hydrochloride By Niosomal Encapsulation", the faculty of pharmacy zagazig university, 2005 More

Department Related Publications

  • Ahmed Samer Zedan, "Physicochemical characterization and dissolution properties of rofecoxib complexes with cyclodextrins", لايوجد, 1900 More
  • Ahmed Samer Zedan, "Preparation and characterization of rofecoxib solid dispersions with polyethylene glycols and urea", لايوجد, 1900 More
  • Mahmoud Mokhtar AhmedIbrahiem, "Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes", لايوجد, 1900 More
  • Amr Selim Ahmed Ali Abu Lila, "Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration", Elsevier, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Tumor-type-dependent vascular permeability constitutes a potential impediment to the therapeutic efficacy of liposomal oxaliplatin", Elsevier, 2012 More
Tweet