Optimization of methotrexate loaded niosomes by Box–Behnken design: an understanding of solvent effect and formulation variability

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 1450-1459
Authors:
Journal: Drug Development and Industrial Pharmacy Drug Development and Industrial Pharmacy Volume: 9
Keywords : Optimization , methotrexate loaded niosomes , Box–Behnken design:    
Abstract:
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential form
   
     
 
       

Author Related Publications

  • Nagia] Ahmed Alameen Elmgrab, "Novel Aqueous solvent based method for protein based nanoparticles.", Association of Biotechnology and pharmacy ®., 2008 More
  • Nagia] Ahmed Alameen Elmgrab, "Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability", A & V Publications India, 2012 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Nagia] Ahmed Alameen Elmgrab, "Ocular controlled delivery of brimonidine using liposomes as a particulate carrier", faculty of pharmac,y zagazig university, 2001 More
  • Nagia] Ahmed Alameen Elmgrab, "Enhancement of Antibacterial Activity of Tetracycline Hydrochloride By Niosomal Encapsulation", the faculty of pharmacy zagazig university, 2005 More

Department Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage", Elsevier, 2013 More
  • Azza Ali Hassan Solyman, "Formulation and evaluation of metformin hydrochloride-loaded niosomes as controlled release drug delivery system", Informa health, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma", MDPI, 2021 More
  • shereen Ahmed Sabry Mohamed Hosney Ismayel, "Experimental Investigation into the Design, Optimization, Toxicity, and Anti-Viral Efficacy of Proliposomes Loaded with Ivermectin Against Infectious Bronchitis Virus Using an Embryonated Chicken Egg Model", MDPI, 2025 More
Tweet