Novel quinazolinone-based 2,4-thiazolidinedione-3-acetic acid derivatives as potent aldose reductase inhibitors

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Journal: Future Medicinal Chemistry Future Science Volume:
Keywords : Novel quinazolinone-based 2,4-thiazolidinedione-3-acetic acid derivatives , potent    
Abstract:
AIM: Targeting aldose reductase enzyme with 2,4-thiazolidinedione-3-acetic acid derivatives having a bulky hydrophobic 3-arylquinazolinone residue. MATERIALS AND METHODS: All the target compounds were structurally characterized by different
    
     
 
       

Author Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone-based rhodanines", Springer, 2017 More

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