Novel 2,4- thiazolidinediones: synthesis, in vitro cytotoxic activity, and mechanistic investigation

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Journal: ُEuropean Journal of Medicinal Chemistry ُُُُElsevier Volume:
Keywords : Novel 2,4- thiazolidinediones: synthesis, , vitro cytotoxic    
Abstract:
Two thiazolidinedione scaffolds different in the position of the thiazolidinedione ring in the molecule were tested for in vitro cytotoxic activity in a panel of human cancer cell lines namely, prostate cancer cells PC-3, breast carcinoma c
    
     
 
       

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Department Related Publications

  • Abdallah Ahmed Abdallah Elshanawany, "Development and validation of RP-HPLC for Simultaneous determination of amiloride,hydrichloride,Atenolol,hydrochlorothiazide and chlorthalidone in their combined mixtures ", لايوجد, 1900 More
  • Hend Kather Abdelhakem Elhamalawy, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY interscience, 2010 More
  • Osama Ibrahim Abdou Elsabagh, "Design, synthesis and cytotoxic activity of novel 1-aroyl -4- (2- chloroethyl) semicarbazides", Khimiko-Farmatsevticheskii Zhurnal, 2007 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF CERTAIN QUINAZOLINE DERIVATIVES", The Chinese Pharmaceutical Journal Vol., 45, No. 2 pp. 109-114, 1993 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS OF 3- SUBSTITUTED (6-BROMO-2-IMIDAZO {4, 5- B} PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYTRIC AGENTS", Zag. J. Pharm. Sci., Vol. 1 No. 1 Nov. Pp 129-139 June, 1993 More
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