Liquid chromatography-tandem mass spectrometric determination of propofol in rat serum and hair at attogram level after derivatization with 3-bromomethyl-propyphenazone

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Journal: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS ELSEVIER SCIENCE BV Volume:
Keywords : Liquid chromatography-tandem mass spectrometric determination , propofol    
Abstract:
A sensitive, selective and precise liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determination of propofol (PRO) in rat serum and hair has been developed. 3-Bromomethyl-propyphenazone was used as derivatization reagen
   
     
 
       

Author Related Publications

  • Soaad Selem Youssef Abdelhay, "Rp-HPLC Determination of Quercetin in a Novel D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Soaad Selem Youssef Abdelhay, "Application of quality by design approach for HPTLC simultaneous determination of amlodipine and celecoxib in presence of process-related impurity", ELSEVIERRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2021 More
  • Soaad Selem Youssef Abdelhay, "Smart UV spectrophotometric methods based on simple mathematical filtration and classical methods for the simultaneous determination of tamsulosin and solifenacin: A comparative study of efficacy and spectral resolution", ELSEVIERRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2021 More
  • Soaad Selem Youssef Abdelhay, "Spectral analysis of severely overlapping spectra based on newly developed mathematical filtration techniques and ratio spectra manipulations: An application to the concurrent determination of dapoxetine and sildenafil in combined dosage form", PERGAMON-ELSEVIER SCIENCE LTD, 2021 More
  • Soaad Selem Youssef Abdelhay, "Utilization of alizarin derivatives for thesensitive spectrophotometric determination of two proton pump inhibitors inpharmaceutical formulations", IOS, 2016 More

Department Related Publications

  • Hisham Abdelaziz Mohamed Hashime, "Quality by design approach for development and validation of a RP-HPLC method for simultaneous determination of co-administered levetiracetam and pyridoxine HCl in prepared tablets", Elsevier, 2018 More
  • Rania Adel Sayed Ahmd, "Development of Simple Green Spectrophotometric and Conductometric Methods for Determination of Cephalosporins in Pure, Pharmaceutical Dosage forms and Human Urine.", Journal of Advances in Chemistry, 2013 More
  • Wafaa Wafaa Alsayed Hassan Abdelatef Abolabn, "Development of Simple Green Spectrophotometric and Conductometric Methods for Determination of Cephalosporins in Pure, Pharmaceutical Dosage forms and Human Urine.", Journal of Advances in Chemistry, 2013 More
  • Magda Youssef Ali Elmamly , "Development of Simple Green Spectrophotometric and Conductometric Methods for Determination of Cephalosporins in Pure, Pharmaceutical Dosage forms and Human Urine.", Journal of Advances in Chemistry, 2013 More
  • Abdallah Abdelaziem Abdallah Shlabi , "Development of Simple Green Spectrophotometric and Conductometric Methods for Determination of Cephalosporins in Pure, Pharmaceutical Dosage forms and Human Urine.", Journal of Advances in Chemistry, 2013 More
Tweet