PARP inhibition ameliorates nephropathy in an animal model of type 2 diabetes: focus on oxidative stress, inflammation, and fibrosis

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Journal: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY SPRINGER Volume:
Keywords : PARP inhibition ameliorates nephropathy , , animal model    
Abstract:
Poly(ADP-ribose) polymerase (PARP) enzyme contributes to nephropathy, a serious diabetic complication which may lead to end-stage renal disease. The study aims to investigate the effect of PARP over-activation on kidney functions in a type
   
     
 
       

Author Related Publications

  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from Hypericum revolutum in Rat Aorta", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance", FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Interference with TGF beta 1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Rp-HPLC Determination of Quercetin in a Novel D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives", PERGAMON-ELSEVIER SCIENCE LTD, 2021 More

Department Related Publications

  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from Hypericum revolutum in Rat Aorta", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance", FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021 More
  • Nora Ahmed Ahmed Mohamed Hsaan, "Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance", FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Interference with TGF beta 1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Rp-HPLC Determination of Quercetin in a Novel D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
Tweet