Optimization of methotrexate loaded niosomes by Box–Behnken design: an understanding of solvent effect and formulation variability

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 1450–1459
Authors:
Mahmoud Mokhtar AhmedIbrahiem
Journal: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY Taylor and Francis Volume: 43
Keywords : Optimization , methotrexate loaded niosomes , Box–Behnken design:    
Abstract:
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential fo
    
     
 
       

Author Related Publications

  • Mahmoud Mokhtar AhmedIbrahiem, "Proniosomal oral tablets for controlled delivery and enhanced pharmacokinetic properties of Acemetacin", AAPS, 2014 More
  • Mahmoud Mokhtar AhmedIbrahiem, "Taste masked orodispersible tablets of cyclosporine self-nanoemulsion lyophilized with dry silica", Pharmaceutical Development and Technology,, 2014 More
  • Mahmoud Mokhtar AhmedIbrahiem, "Pharmaceutical Studies On Certian Multicomponents Colloid Drug Delivery Systems", لايوجد, 1900 More
  • Mahmoud Mokhtar AhmedIbrahiem, "Pharmaceutical Studies On Certian Multicomponents Colloid Drug Delivery Systems", لايوجد, 1900 More
  • Mahmoud Mokhtar AhmedIbrahiem, "Phase Study and Characterization of Certain Developed Multicomponent Colloidal Systems and their Potential Application As Carriers for An Antimicrobial Agent", لايوجد, 1900 More

Department Related Publications

  • Ahmed Samer Zedan, "Controlled release of Diclofenac sodium from matrix tablet formulations.", لايوجد, 1900 More
  • Ahmed Samer Zedan, "Process Analytical Technology: Nondestructive Evaluation of Cyclosporine A and Phospholipid Solid Dispersions by Near Infrared Spectroscopy and Chemical Imaging", لايوجد, 1900 More
  • Azza Ali Hassan Solyman, "Design and in vitro characterization of small unilamellar niosomes as ophthalmic carrier of dorzolamide hydrochloride", Informa health, 2014 More
  • Azza Ali Hassan Solyman, "Formulation and Evaluation of Timolol Maleate Loaded Niosomes as an Ocular Drug Delivery System", Bull.Fac.Pham.Cairo Univ., 2004 More
  • Amr Selim Ahmed Ali Abu Lila, "Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs", Elsevier, 2014 More
Tweet