Optimization of methotrexate loaded niosomes by Box–Behnken design: an understanding of solvent effect and formulation variability

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 1450–1459
Authors:
Mahmoud Mokhtar AhmedIbrahiem
Journal: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY Taylor and Francis Volume: 43
Keywords : Optimization , methotrexate loaded niosomes , Box–Behnken design:    
Abstract:
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential fo
    
     
 
       

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