| Abstract: |
In this investigation, twenty four rabbits of both sexes, 3months oldcollected from a farm in Sharkia for experimental infection with Listeriamonocytogenes, 80 rabbits infected with pasteurellosis and 20rabbit infectedwith ear mange collected from different rabbit farms located in in Dakahliaand Damietta province. All used to study clinical, postmortem findings andhistopathological lesions of these diseases with trials of rei solation andidentification of reisolated isolates.The experimentally infected rabbits with Listeria monocytogenes viaintraperitoneal route showed clinical signs in the form of poor appetite,depression, ruffled fur, diarrhea soiled hind quarter, respiratory signs, eyeaffection followed by emaciation then deaths. Macroscopically, severecongestion in liver, spleen, lungs, uterus, brain beside engorgement ofmesenteric blood vessels were noticed. Sometimes, retention of urine andpetechial and / or ecchymotic subcapsular hemorrhages in kidneys was alsodetected two weeks PI. Also, some infected rabbits showed conjunctivitis inaddition to the presence of straw colored fluid in the abdominal cavity.Microscopically, Brain showed perivascular lymphocytic cuffing inVirchow robin space with focal lymphocytic aggregation in surroundingtissue and congested blood vessels were predominant 15 days PI. Congestionin meningeal blood vessels was also detected. Liver showed multiple areasof necrotic changes in the hepatic parenchyma. Proliferative bile ductules inportal area was also detected. Moreover, hyperplastic kuffers cells withvarious degenerative changes was also noticed. Focal congestion insinusoidal blood vessels 7and 15daysPI was also detected. Lungs showedfocal thickeneing of some interalveolar septa by lymphocytes and some
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