Clinicopathological Studies on The Effect of Probiotic in Oreochromis Niloticus

This study was conducted to evaluate the effect of probiotic(Biogen) and enrofloxacin on growth performance, hematologicaland biochemical alterations as well as immune response in o.niloticus experimentally infected with Aeromonas hyDROPhila.During this study, a total number of 280 apparently healthyo. niloticus were used for experimental infection, trials of treatmentby using pro biotic and enrofloxacin which were divided into 7groups each of 40 fish. Gp. (1) was kept as normal control. Gp.(2)was administered Biogen (0.5 gm I kg feed) from 1- 60 days. Gp.(3) was administered Enrotryl (2mg I litre drinking water) atl ihdays for 5 successive days. Gp. (4) was infected intraperitoneal with0.5 ml of A.hyDROPhila (4xl08 cfu Iml) at 14th day. Gp.(5) wasadministered Biogen (0.5 gm I kg feed) for 60 days and infected lIPwith 0.5ml of A.hyDROPhila (4x108 cfu Iml) atl4th day. Gp. (6) wasinfected lIP with 0.5ml of A.hyDROPhila (4x108 cfu /ml) at 14th dayand treated at the 1 ih days with Biogen (0.5 gm I kg feed) for 5successive days. Gp.(7) was infected lIP with 0.5ml of A.hyDROPhila(4x108 cfu Iml) at 14th day and treated with Enrotryl (2mg I litredrinking water) at 1 ih day for 5 successive days.Fish in each group were weighted every 2 weeks to determinethe [mal body weight, body. gain % and the specific growth rate at