Clinicopathological Studies On The Effect Of Fiuoride Toxicosis In Chickens

Fluoride is a naturally occurring element, fluoride compounds areconstituents of minerals in rocks, soils, air, natural waters and foods. In theother way aluminum the most abundant metal in the Earth’s crust, is presentin a variety of foodstuffs and medications (e.g. vaccines and antiacids) aswell as in domestic water supplies. Aluminum compounds form less solublecomplexes with fluoride and decrease the absorbability of fluoride orneutralize the hydrogen fluoride produced in the stomach.The present work was performed to study the effect of sodiumfluoride and aluminum sulphate on clinical signs, growth performance,hematological and biochemical changes and correlate them withpathological changes in balady chickens. In addition to the evaluation of aluminum sulphate as a treatment of sodium fluoride toxicity.This study was carried out on one hundred and fifty (one day old)balady chickens. Chickens were divided into six equal groups (each group of25 chickens); first one fed on normal ration (control group); second one fedon ration contains 800 ppm of sodium fluoride; third one fed on rationcontains 1600 ppm of sodium fluoride; fourth one fed on ration contains 640ppm aluminum sulphate; fifth one fed on ration contains 800 ppm(sodiumfluoride)+ 640 ppm (aluminum sulphate) as (1st treated group) and sixth onefed on ration contains 1600 ppm (sodium fluoride)+ 1280 ppm (aluminumsulphate) as (2nd treated group) from one day old to the end of experiment(seven weeks).