The experimental work of the present study was carried out in the rabbit’s farm of Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt from October to December 2008.A total number of 56 weanling New Zealand rabbits of 35 day old, were divided into seven groups (8 each). The first group was used as a control and other groups supplemented with different types of feed with addition of enzyme to some groups as following The experimental rations were offered ad \libitum twice daily. Rabbits were individually weighted to the nearest gram every week. At the end of experimental period, three representative rabbit’s samples from each feeding group were randomly taken to studyTen digestion trials were conducted to determine the digestion coefficient of nutrients and nutritive value of the experimental diets.• The experimentally affected chickens with visceral gout ( exposed to sodium bicarbonate 2% for 3 days in drinking water )and then treated with allopurionl and / or dl-methionine showed a great improvement in body weight .5) Effect on hematological picture:• Chickens experimentally affected with visceral gout (exposed to sodium bicarbonate for 3 and for 10 days in drinking water) evoked significant changes in erythrocyte count, packed cell volume and hemoglobin concentration, blood pH.• The experimentally affected chickens with visceral gout ( exposed to sodium bicarbonate 2% for 3 days in drinking water )and then treated with allopurionl and / or dl-methionine showed a great improvement in erythrocyte count, packed cell volume and hem• Chickens experimentally affected with visceral gout (exposed to sodium bicarbonate 2% for 10 successive days in drinking water) and at the same time treated with allopurinol and / or dl- methionine showed mild improvement in erythrocyte count, packed ce6) Effect on serum biochemical parameters:• Chickens experimentally affected with visceral gout (exposed to sodium bicarbonate for 3 and for 10 days in drinking water) evoked significant increase in uric acid and creatinine levels compared with non affected non treated groups.• The experimentally affected chickens with visceral gout ( exposed to sodium bicarbonate 2% for 3 days in drinking water )and then treated with allopurionl and / or dl-methionine showed a great improvement in uric acid and creatinine levels .• Chickens experimentally affected with visceral gout (exposed to sodium bicarbonate for 3 and for 10 days in drinking water) evoked significant changes in sodium, potassium and chloride levels compared with non affected non treated groups• The experimentally affected chickens with visceral gout ( exposed to sodium bicarbonate 2% for 3 days in drinking water )and then treated with allopurionl and / or dl -methionine showed a great improvement in sodium, potassium and chloride levels .• Chickens experimentally affected with visceral gout (exposed to sodium bicarbonate for 3 and for 10 days in drinking water) evoked significant increase in AST, ALT, ALP activities compared with non affected non treated groups.• The experimentally affected chickens with visceral gout ( exposed to sodium bicarbonate 2% for 3 days in drinking water )and then treated with allopurionl and / or dl -methionine showed a great improvement in AST, ALT, ALP activities.• Chickens experimentally affected with visceral gout (exposed to sodium bicarbonate for 3 and for 10 days in drinking water) evoked significant changes in total protein, albumin, and globulin levels compared with non affected non treated groups.• The experimentally affected chickens with visceral gout ( exposed to sodium bicarbonate 2% for 3 days in drinking water )and then treated with allopurionl and / or dl -methionine showed a great improvement in total protein, albumin, globulin levels.7. Histopathological findings:• Chickens experimentally affected with visceral gout demonstrated severe renal, cardiac, hepatic and lung lesions. Chickens experimentally affected with visceral gout and treated with allopurinol and / or dl-methionine showed mild degenerative changes wi