Synthesis of Acyclovir and HBG Analogues Having Nicotinonitrile and Its 2-methyloxy 1,2,3-triazole

Faculty Science Year: 2011
Type of Publication: ZU Hosted Pages: 340–352
Authors:
Ahmed Heussein Mostafa
Journal: Nucleosides, Nucleotides and Nucleic Acids Taylor & Frncis group Volume: 2011
Keywords : Synthesis , Acyclovir , HBG Analogues Having Nicotinonitrile , Its 2-methyloxy    
Abstract:
Reaction of pyridin-2(1H)-one 1 with 4-bromobutylacetate (2), (2-acetoxyethoxy)methyl bromide (3) gave the corresponding nicotinonitrile O-acyclonucleosides, 4 and 5, respectively. Deacetylation of 4 and 5 gave the corresponding deprotect
    
     
 
       

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