Risk Assessment of Some Environmental Pollutants In Sharkia Province

The present study was carried out on two main experimentsExperiment (I): Rice straw burning studyThirty albino rats of both sex weighing 150-250gm were used in this study. They randomly divided into 3 experimental groups.1- Control group (n =10)Rats were exposed to atmospheric air.II- Smoke exposed group (n =20)This group was divided into 2 subgroups according to the duration of exposure to smoke.1st subgroup (n=10), Rats were exposed to a smoke produced from burning of rice straw for 15 day (5 hours daily).2nd subgroup (n=10), Rats were exposed to a smoke produced from burning of rice straw for 30 day (5 hours daily).The animals were anaesthetized with diethyl ether. Then the anterior chest wall was removed and the blood samples which used for biochemical determination of blood gases analysis. The tissue specimens were obtained after death of the animal for histopathoExperiment (II): Di-n-butyl phthalate studiesA). Developmental toxicity studyThis experiment was carried out on thirty adult female rats weighing 180-250gm. The pregnant rats were distributed on a random basis into 3 groups of 10 pregnant rats in each one.• Group I (n=10): This group received the corn oil only (Control group).• Group II (n=10): The pregnant rats were administered DBP daily by gastric intubation at a dose of (1/10 LD50) 800mg/kg body weight from day 6th to day 15th of gestation.• Group III (n=10): The pregnant rats were administered DBP daily by gastric intubation at a dose of (1/20 LD50) 400mg/kg body weight from day 6th to day 15th of gestation.