Synthesis and Analgesic Activity of Some New Pyrazoles and Triazoles Bearing a 6,8-Dibromo-2-methylquinazoline Moiety

Faculty Science Year: 2011
Type of Publication: ZU Hosted Pages: 10187-10201
Authors:
Ahmed Heussein Mostafa
Journal: Molecules www.mdpi.com Volume: 2011
Keywords : Synthesis , Analgesic Activity , Some , Pyrazoles and Triazoles    
Abstract:
2-(6,8-Dibromo-2-methylquinazolin-4-yloxy)-acetohydrazide (4) was prepared by the reaction of 6,8-dibromo-2-methylbenzo-[d][1,3]oxazin-4-one with formamide to afford quinazolinone 2, followed by alkylation with ethyl chloroacetate to give
    
     
 
       

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