Design, synthesis and in-vitro antitumor activity of novel phthalazin-1,4-dione/chalcone hybrids and phthalazin-1,4-dione/pyrazoline hybrids

Faculty Pharmacy Year: 2015
Type of Publication: ZU Hosted Pages: 1154-1166
Authors:
Nermeen Awny Ahmed Mohamd
Journal: Journal of Chemical and Pharmaceutical Research JCPRC5 Volume:
Keywords : Design, synthesis , , in-vitro antitumor activity , , novel    
Abstract:
In continuation of our study of phthalazinones with antitumor activity, several new phthalazin-1,4-diones based on the structure of vatalanib (PTK787) were designed and synthesized. The cytotoxicity of the final compounds was tested in vitr
    
     
 
       

Author Related Publications

  • Nermeen Awny Ahmed Mohamd, "Synthesis of some new Pyrazole Derivatives of Possible Biological Interest", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrimidine derivatives ", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrazole derivatives", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Utility of 2-Hydrazino-4,6-Dimethyl –Pyrimidine in Heterocyclic Synthesis ", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "A novel method for the synthesis of 1-aryltetrahydroisoquinolines", Elsevier Ltd, 2017 More

Department Related Publications

  • Etedaal Hassan Mohamed Abdulaal, "14. Reaction of 2-Ethyl Thiohydantions with Anthranilic Acid", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "9. A New Derivatives from Thiolanes and Thietanes; ", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "10. Anti-inflammatory Activity of Some Novel-s- Triazole Derivatives", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "21. Synthesis, Antimicrobial and Antiviral Activity of 1,8-Dioxodecahydroacridine Derivatives", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "25. Synthesis And Anti-inflammatory Activity of Some Novel Quinazoline Derivatives", لايوجد, 1900 More
Tweet