Synthesis of Novel Imidazole and Fused Imidazole Derivatives as Cytotoxic and Antimicrobial Agents: Molecular Docking and Biological Evaluation

Faculty Pharmacy Year: 2015
Type of Publication: ZU Hosted Pages: 36-45
Authors:
Nermeen Awny Ahmed Mohamd
Journal: International Journal of Pharmacy and Pharmaceutical Sciences Innovare Volume:
Keywords : Synthesis , Novel Imidazole , Fused Imidazole Derivatives    
Abstract:
The objective of this work is to synthesize novel imidazole and fused imidazole derivatives using 4-arylidene-2-hydrazino-1-phenyl imidazolin-5-ones (5a-c) as key intermediate. The structure of the newly synthesized compounds was characteri
    
     
 
       

Author Related Publications

  • Nermeen Awny Ahmed Mohamd, "Synthesis of some new Pyrazole Derivatives of Possible Biological Interest", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrimidine derivatives ", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrazole derivatives", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Utility of 2-Hydrazino-4,6-Dimethyl –Pyrimidine in Heterocyclic Synthesis ", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Design, synthesis and in-vitro antitumor activity of novel phthalazin-1,4-dione/chalcone hybrids and phthalazin-1,4-dione/pyrazoline hybrids", JCPRC5, 2015 More

Department Related Publications

  • Tarek Mohamed Salah Rashad, "Alteration of Salmonella enterica Virulence and Host Pathogenesis through Targeting sdiA by Using the CRISPR-Cas9 System", Multidisciplinary Digital Publishing Institute, 2021 More
  • Tarek Mohamed Salah Rashad, "Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.", Wiely, 2019 More
  • Hanan Abdelraziek Abdelfattah Ali Hamied, "" تشييد بعض مشتقات البيرميدين الجديدة ذات النشاط الأقربازيني "", 2024 More
  • Tarek Mohamed Salah Rashad, "Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold", 2020 Elsevier, 2020 More
  • Hanan Abdelraziek Abdelfattah Ali Hamied, ": A novel method for the synthesis of 1-aryltetrahydroisoquinolines", England, 2016 More
Tweet