Efficacy of some antimicrobials in chickens

Chlormaphenicol, the first broad spectrum antibiotic to be discovered has broad spectrum of activity against both gram positive and gram negative bacteria. Florfenicol is a novel structure analogue of chloramphenicol, it differs from chloramphenicol by thEscherichia coli (E. coli) affects poultry industry causing major economic losses achieved by high morbidity and mortality, loss of body weight and decrease egg production. So control of this microbe is very important for poultry industry.The present study was conducted to evaluate the antibacterial effect of chloramphenicol or florfenicol in healthy and experimentally infected chickens with E. coli. The sensitivity of isolated E. coli strains of avian origin is investigated in vitro to di