some studies on babesia vaccines in cattle

Experimental trial for vaccination was conducted, where, two groupsof susceptible calves (GI and GII) were vaccinated against B. bovis usingtwo types of killed vaccines ( erythrocytic and merozoite vaccinerespectively). A third group (Gill) was kept as non vaccinated controls.Vaccinated animals responded normally to vaccination. The level of serumantibodies against B. bovis was in the first group (erythrocytic vaccine groupGI) higher than that of the second group (merozoite vaccine group GII).No clinical adverse reactions could be observed in vaccinated animalsand the body temperatures were in their normal ranges as in control noninfected group.The two tested vaccine types proved their safety as no detection ofparasitaemia in blood of vaccinated animals throughout an observationperiod of 42 days post vaccination.The vaccinated animals in the first group (GI) could withstandchallenge with the virulent strain ofB. bovis more efficiently than those ofthe second group (GII). The third group (control group GIll) developed thepicture of infection with babesiosis after infection with the virulent strain It could be concluded that the erythrocytic vaccine in regarding toimmunity and easier method of preparation c(;mld be applied for vaccinationof cattle against B. bovis.