Studies on modern suture materials in experimental animals

This work aimed to evaluate a modem suture materialpolyvinylidene fluoride (PVDF) for oral cavity reconstruction 111comparison to other suture materials as silk, catgut and vicryl.A number of 60 dogs were used in this study, divided into 3groups each of 20 dogs, each group divided into 4 subgroups (A, B, Cand control). All experimental dogs received 6 incised wounds inbuccal cavity (left and right side at gum, check and tongue). Theinduced wounds of the left side was closed by PVDF, while the rightside was closed by silk, catgut and vicryl. The control subgroup waskept without sutures.The animals were examined clinically at 4th, th for first group, thand 14th for second group and 7th, 14th and 21st days for third grouppost-suturing. Specimens were taken for histopathologicalexamination from all animals after sacrificing at 7, 14 and 21 dayspost operative.After post operative 4th day there was no apparent differenceamong suture materials used. Good healing status with littleinflammatory reaction were seen in PVDF suturing after 7 days, whilepartial healing and marked inflammatory reaction in other suturematerials.At 14 days PVDF showed complete healing, little inflammatory