A Biochemical Study On Hypolipidemic Factors In Rats

A total of 90 male adult albino rats weighing 150±20 gm were used. Animals were kept at constant environmental and nutritional conditions during the experimental periods and were living on their food and water ad- libitum. The food was consisted of bread,10 rats were sacrificed and the rest 30 rats were subdivided into threeequal groups, each of ten: Subgroup (a): hyperlipidemic rats and received L-carnitine (Sigma Chemical St. Louis, MO) in a dose of 6.3 mgllOO gm B.w., daily for 8 weeks. Subgroup (b): hyperlipidemic rats. and received chromium piclionate in a dose of3.61lgand 3.6 ug chromium piclionatellOO gm B.W. daily for 8 weeks. Ill-Group (Ill): STZ-diabetic rats (40 rats):Rats were injected intraperitoneally with Streptozotocin (SigmaChemical St. Louis, MO) in a dose of 50 mg/kgm B.W. dissolved in 50 mmollL citrate buffer, pH 4.5. After 12 days following STZ-administration,