The P-450 enzymes usually catalyze oxidative metabolism ofxenobiotics as a part of the process of inactivation and elimination from thebody. The activity of CYP enzymes may sometimes lead to the formationof reactive metabolites with toxic or carcinogenic consequences. It hasbecome evident that xenobiotics-metabolizing CYP enzymes may also beinvolved in vital cell functions affecting growth, differentiation andhomeostasis.About 150 compounds that could be characterized as P AH were foundin tobacco smoke and hundreds were found in surrounding environment.Chemical constituents of P AH readily cross the placenta and producevarious forms of embryo toxicity such as small-for-date babies andintrauterine demise (miscarriage and stillbirth). Furthermore, the combinedands in transmission of parasites to the farm animals. The materials of this work included animal stables, manure heaps, soil and grass from cultivated lands. During this study, 586 samples were examined . These samples included 156 stable samples, 240 saeggs and oocysts using sedimentation and floatation technique while, the nematode larvae were isolated using Baermann technique. Grass samples were examined for nematode larvae by sedimentation technique. Mites were isolated from manure manure was examineheaps, soil samples and grass samples respectively