Effect of Chemotherapeutic Drugs on Immune Response for Newcastle Disease And Gumboro Disease Vaccines in Chickens And Its Relation Feeding Programs

A. Immune response in vaccinated chickens was estimatedafter treatment with gentamycin, streptomycin,enrofloxacin and sulphaquinoxalin, the GM of ND HIantibody titers and NA titers were:1- A significant decrease in GMT of HI and NA titers in group ofchicken treated with gentamycin at 15 and 30 days of age and fed22% protein, the titer was (57 ± 3.53 - 61 +3.97) and (4.0 +0.24 -4.5 ± 0.29), in control group (92 ± 4.6 - 106 ± 5.3) and (6.5 ± 0.29- 7.0 +0.39), respectively while the protection percent was (60%and 70%).2- A significant decrease in GMT of HI, NAT in group of chickentreated with gentamycin at 15 and 30 days of age and fed 18%protein, the titer was (53 ± 3.29 - 57 ± 3.71) and (3.8 ± 0.23 - 4.0+0.26), in control group (92 ± 4.6 - 106 ± 5.3) and (6.5 ± 0.29-7.0 ± 0.39), respectively while the protection percent (60%).3- A significant decrease in GMT of HI and NA titer in group ofchicken treated with streptomycin at 15 and 30 days of age andfed 22% protein, the titer was (65 ± 4.03 - 70 ± 4.55) and (4.8 ±0.29 - 5.3 +0.34), in control group (92 ± 4.6 - 106 ± 5.3) and (6~5+ 0.29 - 7.0 ± 0.39), respectively, while the protection percentwas (70% and 75%).