| Abstract: |
Ninety balady chickens of 60 days old were divided into 7 groups tostudy the pathological findings in vaccinated chickens with some fowlcholera vaccines and challenged post vaccination with Pasteurellamultocida. These chickens were divided into 7 groups. Groups 1,4 and 7consisted of 10 chickens in each group, while groups 2,3,5 and 6 consistedof 15 chickens in each group. Each chicken in groups 1, 2 and 3 wasvaccinated with 0.5 ml from the oil adjuvant vaccine. one month later, eachchicken in group 3 was given boaster dose. The vaccinated chickens werechallenged with virulent strains of P. multocida, 2 weeks after the firstvaccination in group 2 and 10 days after the boaster dose in group 3. Thechickens were sacrificed 5, 10 and 15 days PV in group 1 or PC in groups 2and 3. The chickens in groups 4,5 and 6 were treated as groups 1,2 and 3respectively by using the live avirulent vaccine via the wing web routeThe chickens in group 7 were infected intramuscularly with virulent P.multocida and sacrificed 5, 10 and 15 days PI.The mortality rates were 6.7%, 10%, 20% and 100% in chickens ofgroups 2,4,5 and 7 respectively. The detectable clinical signs in theprevious groups were depression, anorexia, greenish or yellowish diarrheaand some respiratory manifestations. The intensity and duration of thesesigns varied according to the type of treatment.The lesions in chickens of group 1 (oil adjuvant vaccine) wereminimal and concluded in moderate activation of the immune system andmild reversible lesions in other organs. The chickens of group 4 (live
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