Effects of Aome Aminoglycosides in chickens

The present work was carried out to study the efficacy of kanamycin and gentamicin against experimentally E. coli infected chickens and studying the side effects that could be reflected on liver and kidney functions and the histopathological changes involdiarrhea DROPped head and closed eyes) were recorded. Treatment with therapeutic regimen of both kanamycin and gentami-cin, evoked a slight decline in gross pathological lesions.Fourteen day posttreatment the birds displayed complete recoveryfrom gross pathological lesions with mild clinical signs in case of kanamy-cin treated group but not ingentamicin, treated one . B) Effect of kanamycin and gentamicin on blood constituent ofchickens. Healthy chicks treated with kanamycin displayed no changes inblood constituents. Meanwhile, the birds treated with gentamicin showeda significant decrease of RBCs count, haemoglobin concentration