Effects of High Dose Methotrexate and Delayed Elimination on Myelotoxicity Progression in Children with Acute Lymphoblastic Leukemia

Faculty	Pharmacy	Year:	2017
Type of Publication:	ZU Hosted	Pages:	1-7
Authors:	Staff Zu Site Abstract In Staff Site
Journal:	Afro-Egypt J Infect Endem Dis Afro-Egypt J Infect Endem Dis	Volume:	7

Keywords :	Effects , High Dose Methotrexate , Delayed Elimination
Abstract:	Background and study aim: Methotrexate (MTX) as an antineoplastic agent inhibits dihydrofolate reductase. The frequency of high dose methotrexate (HDMTX) associated toxicity is variable. In this study we investigate the frequency of myelosu