Pathologic studies on bovine viral diarrhea

Virological studies revealed recovery of the virus from the internal organs of infected animals. Also the virus was isolated from nasal and rectal swabs. The seroconversion (by using serumneutralization test) in infected animal confirmed the results. The serological survey in serum samples collected from 200 infected animals indicating an incidence of (60%) positive cases.Twenty cases from both six (9 Friesian calves aged 3-8 months, 4 cows aged 18-30 months, 6 buffalo-calves aged 3-7 months and 1 adult buffalo aged 4 years) proved to be BVD positive and dead after a period of illness were examined The pathological study ohigh risk of BVD in farm animals specially calves. The clinicalmanifestations were mainly gastro-intestinal and respiratory in natureincluding diarrhea, gastro-intestinal crump, excessive salivation,congestion and erosions on the tongue and gum, nasal discharge, cough and lacrimation, Grossly the tangue, esophagus, reticulum and abomasumshowed congestion, erosion and ulceration. The intestine wascongested and contains blood mixed with faceases, beside ulcerative and necrotic changes. Mesenteric lymph node and spleen appeared larger in size than the normal. The lungs were,’ edematous,emphysematous with red hepatization. Liver was yellowish in col