Pharmacological studies on enrofloxacin Avitryl in chickens

Enrofloxacin residues in raw, boiled and fried eggs were investigatedafter administration of its recommended dose (10 mg/kg b.wt./day) orally for3 or 5 successive days to laying hens. Enrofloxacin residues were detectedin albumin of raw eggs of 3 days treated group on the 2nd day of drugadministration (O.14±0.01 ug/gm) with maximum concentration on the 1 stday post drug withdrawal (0.19±O.01 ug/gm), then disappeared on the 4thday. In the yolk, it was detected on the 1~ day post drug withdrawal (0.13ug/gm) then disappeared on the 5th day. For 5 days treated group,enrofloxacin residues in albumin of raw eggs were detected on the 2nd dayof drug medication (0.13 ug/gm) which increased gradually till reached itsmaximum concentration on the 4th and 5th day of drug administration (0.20ug/gm) , then disappeared on the 4th day post drug withdrawal. In the yolk,the residues were detected on the 4th day of drug medication (0.14±0.OIug/gm) then disappeared on the 5th day post drug withdrawal.The effect of heat on enrofloxacin residues on boiled or fried eggs ofthe same previous egg samples indicated that,’ no drug residues could beThe fertility% of incubated eggs of 3 and 5 days treated and controlgroups was 93.3 %, 93.8% and 91. 7% respectively during treatment and