An efficient method for the preparation of peptide alcohols

Faculty Pharmacy Year: 2009
Type of Publication: Article Pages: 4444-4447
Authors:
Gyanda, Kapil, Katritzky, Alan Roy, Abo-Dya, Nader Elmaghwry, Tala, Srinivasa Rao, Abdel-Samii, Zakaria Kamel
DOI: 10.1039/b905730g
Journal: ORGANIC \& BIOMOLECULAR CHEMISTRY ROYAL SOC CHEMISTRY Volume: 7
Research Area: Chemistry ISSN ISI:000270795700015
Keywords : , efficient method , , preparation , peptide alcohols    
Abstract:
N-Protected LL-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d') and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(alpha-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a') and N-protected(alpha-dipeptidoyl) benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.
    
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