Studies on Rift Valley Fever Among Animals In Egypt

All prepared vaccines either alum or oil emulsion adjuvant I univalent RVF alum gel,combined (RVF+FMD) alum gel, RVF oil emulsion vaccine, FMD oil emulsion vaccine and combined (RVF+FMD)oil emulsion vaccine were were protected animals against challenge wifoun§’ safe an potent with (EDSO 0.0013/0.1 ml foralum ad j uv a n t ) an (O.Ol/ml.) for oil adjuvant.2· Vaccination of sheep with various prepared vaccine’ pro-ved that those vaccinated with oil emulsion either un i v a-lent or combined ones gives 100% AGPT starting from the 2ndweeks while gel vaccine give 100% at the 4th week postvaccination. Concerning NI again oil emulsion vaccine gives a protective ti ter started from the 2nd week( 2.75)CF ti ter was _ found higher (6.0 and 5.6) than those ofsheep vaccinated with gel vaccine in the 2nd week. Allvaccines protect~~,sheep against challengewitha viruelent RVFvir u s ( tit e r ofl 0 6 T CID 5 0 / m 1 .) e x c e p t t h 0 s e vac c i n ate d wit h gel v ac ci n e 2% of virus isolated from the serum could berecorded While the control non vaccinated groups givea result of virus isolation of 64.2% from serum samples, 21.4%from both nasal and faecal swabs. No lesions could be observed on the feetand primary lesions at the siteof injection on sheep vaccinated with oil vaccine cont- aining FMD virus when challenge with 104 MIPLD50/ml FMDvirus.