Studies on certain locality available tranquilizers and anaethetics in animals

The present study was carried out on 80 clinically healthy volunteer dogs of different age, sex, and body weight. The animals were divided into 8 groupseach of 10 dogs. The pharmacologioal and clinioal effects of the used anae stihetr ic s (Thiopentone &Ketnlnr) and tranquilizers (Stellanile & Sparine) were studied.Some serum biochemical variations and blood changes before and after anaesthesia were alsorecorded. Intravenous thiopentone anaesthesia in a doseof 25.15 mg/kg. b.w~ proved to be n satisfactory short acting general anaesthetic for the dog~During anaesthesia the pulse rate was increased while respiration and temperature decreased, butreturned to normal. ~ntol2& caused a decrease ln erythrocytes, haemoglobin, P.C.V.,and leukoc.ytswhich regained its normality later on~ The increase in G.P.T., crentinine and the decrease in G.O.T.,Total bilirubin, Total protein, and B.U~N., indicated no pathological changes in the liver and kidneyfunct ions. The premedication of thiopentone with stellaniledecreased the amount of annesthetic required .