Clinicopathological studies on the phenylbutazone in animals

Phenylbutazone is one of nonsteriodal anti-inflammatory drug , (NSAID) . Inspite of having strong treating of musculoskeletal disorders, spondylities in most animals and successfully for the management of painful rheumatic arthritis diseases, related disoharmful effects on other body organs specialy liver, kidney, lung. Thereforecurrents this study . Ninty male albino rats were used in two experiments in this study . The first experiment consist of 45 rats, 30 of them were orally administered phenylbutazone as initial therapeutic dose (41 mg/kg B.wt) as single dose then maintaina