Clinicopathological Studies on Some Veterinary used Tranquilizers

Tranquilizers are drugs usually cause sedation without cause drowsiness, they are widly used in veterinary practice as preanaesthetics and used in human being as antiemetic andanticonvulsant . The use of such kind of drugs has become widly spread only sinrepresenting phenothiazine derivatives and xylazine hydrochloriderepresenting neuroleptics . In the present work we studied the effect of either two drug on clinicobiochemical, haematological and histopathological effect on liver, kidney, heart and spleenxylazine hydrochloride at a dose of 0.05 mg / Animal injected intra peritoneally for 1 , 2, 3 , 7, 14 , 2 1 and 28 days, the remainder 35 animals were left as control The same was done- with the second group which was treatedwith chlorpromazine hydrochlorid injected intra peritoneally ata dose of 10 mg / kg .